Gemazocine
From Wikipedia, the free encyclopedia
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| Systematic (IUPAC) name | |
| 10-(cyclopropylmethyl)-1-ethyl-13,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2,4,6-trien-4-ol | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 54063-47-7 |
| ATC code | None |
| PubChem | CID 219096 |
| ChemSpider | 189916 |
| Chemical data | |
| Formula | C20H29NO |
| Mol. mass | 299.450 g/mol |
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Gemazocine (R-15,497), also known as cyclogemine, is an opioid antagonist of the benzomorphan family which was never marketed.[1][2] It has weak partial agonist properties at the opioid receptors but is generally antagonistic in its effects.[3]
See also [edit]
References [edit]
- ^ Macdonald, F. (1997). Dictionary of Pharmacological Agents. CRC Press. p. 955. ISBN 978-0-412-46630-4. Retrieved 22 April 2012.
- ^ Gelders, Y. G.; de Ranter, C. J.; Schenk, H. (1979). "Structural Studies of Substituted 6,7-Benzomorphan Compounds. I. The Absolute Configuration of (−)-2-Cyclopropylmethyl-2'-hydroxy-5-ethyl-9,9-dimethyl-6,7-benzomorphan (Gemazocine) Hydrobromide". Acta Crystallographica B 35 (3): 699–703. doi:10.1107/S0567740879004477.
- ^ Freye, E.; Hartung, E.; Schenk, G. K. (1983). "Bremazocine: An Opiate That Induces Sedation and Analgesia without Respiratory Depression" (pdf). Anesthesia and Analgesia 62 (5): 483–488. PMID 6301311.
