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Rylance is the daughter of Judge John Rylance QC, a circuit judge.
At the age of eighteen, Rylance was recruited by a model scout who met her in a pub on the Portobello Road, London, during the Notting Hill Carnival. This led to a short modelling career which included a Coca-Cola commercial. She hoped this would be a way into acting. However, she accepted a place at Oxford Brookes University and graduated three years later in politics and publishing. She then trained at the London Academy of Music and Dramatic Art. While she was a drama student, she was a regular in the audience at the Gate Theatre.
In 2008, she met Canadian doctor Greg Bailey in Los Angeles and in 2009 was living with him in an apartment in Knightsbridge, London. The same year, she spent a month in Antarctica and several weeks in Peru working in an orphanage.
Lives between London and LA.
In 2011 did a tandem skydive to raise money for CRISIS charity.
In 2012 she was reported to be producing her first movie, a Second World War film set in Eastern Europe
Is involved with Plan Zheroes, a food charity aiming to stop the waste of food in London.
Georgina Rylance's first screen role was in Howard Davies's television movie Armadillo (2001), in which her character was Amabel.
In the movie Puritan (2006), an official selection at the Berlin 2005 Fantasy FilmFest and the London 2006 Fantasy Filmfest, she starred alongside Nick Moran.
She was a guest star in the first and second episodes of the NBC show Crusoe (2008).
Producing her first movie, a WW2 movie set in Eastern Europe (reference Daily Mail 2012)
She starred alongside Ed Stoppard in the short film 'Scooterman' which won awards at Cannes, LA, Palm Springs and Santa Barbara Film Festivals