The history of Ghamd goes back to the pre-Islamic era, and many members of Ghamd joined the forces of the early Muslim empire. As a matter of fact Alghamdi tribe belongs to the same root, Azd, as Alansars. Alansars are the two tribes inhabited Madena, named Aws and Khazraj that sheltered, supported, and fought with the prophet Mohammed (Peace and Blessing Be Upon Him) in the early days of Islam when he and his early companions from Makkah had to leave it for Madenah. Many members of Alghamdi tribe were companions of the prophet of Islam (Peace and Blessing Be Upon Him) and fought with him to defend Islam and Muslims. Like most other tribes in the southwestern region of the country, Ghamd is divided into three large groups, based on geography and lifestyle: the mountaineers (sarat) in the central highlands of Al-Baha and 'Asir, the bedouins (badyah) in the desert regions to the east, and the tohm who inhabit the narrow plain of Tihama on the Red Sea coast.
- Abdul Rahman Al-Ghamdi (born 1974), Saudi terror suspect
- Abdulrahman AlGhamdi, Saudi footballer.
- Ahmed al-Ghamdi (1979–2001), Saudi hijacker of United Airlines Flight 175
- Hamza al-Ghamdi (1980–2001), Saudi hijacker of United Airlines Flight 175
- Khalil Al Ghamdi (born 1970), Saudi football referee
- Omar Al-Ghamdi (born 1979), Saudi footballer
- Othman Ahmad Othman al-Ghamdi, Kandahar detention facility detainee
- Saeed al-Ghamdi (1979–2001), Saudi hijacker of United Airlines Flight 93
- Ahmed al-Haznawi(1980–2001), Saudi hijacker of United Airlines Flight 93
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