|Date of birth||March 17, 1960|
|Place of birth||Pisa, Italy|
|Date of death||November 6, 2002(aged 42)|
|Place of death||Pisa, Italy|
|Height||1.86 m (6 ft 1 in)|
|Playing position||Centre back, libero|
|* Senior club appearances and goals counted for the domestic league only.
† Appearances (Goals).
Born in Pisa, Signorini started his career playing for his home team, Pisa S.C. of Serie C1, and successively for Pietrasanta, Prato, Livorno, Ternana and Cavese before joining A.C. Parma, with Arrigo Sacchi as coach. He quickly became a key player for Parma, and was successively signed by Nils Liedholm's A.S. Roma, and then to Genoa in 1988, after personal requests by coach Francesco Scoglio. He played seven seasons for Genoa, all seven years as team captain, a hard defender and definitely a fan favourite. He is remembered as one of the last (and best) Italian sweepers. In recent years; he was a vital member of the Genoese "dream team" which managed to reach the semi-finals of the 1991–92 UEFA Cup and became the first Italian team to beat Liverpool F.C. on their Anfield Road home turf.
After having ended his playing career, Signorini started a managing career working for Pisa, and serving as joint caretaker manager during their 1997–98 Serie C2 campaign, However, he soon discovered he was suffering from amyotrophic lateral sclerosis, also known as Lou Gehrig's disease, an illness that slowly forced immobility, paralyzing all his muscles. He died on November 6, 2002, in his Pisa home. In his honour, the #6 Genoa CFC jersey, worn by Signorini during his time for the rossoblu, has been retired.