Ginkgolide
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Ginkgolides are biologically active terpenic lactones present in Ginkgo biloba. They are diterpenoids with 20-carbon skeletons, which are biosynthesized from geranylgeranyl pyrophosphate.[1]
| R1 | R2 | R3 | |
| A | OH | H | H |
| B | OH | OH | H |
| C | OH | OH | OH |
| J | OH | H | OH |
| M | H | OH | OH |
Gingkolide B may be effective as preventive treatment in reducing migraine attack frequency.[2]
[edit] See also
[edit] References
- ^ Niels H. Andersen, Niels Johan Christensen, Peter R. Lassen, Teresa B.N. Freedman, Laurence A. Nafie, Kristian Strømgaard, Lars Hemmingsen (February 2010). "Structure and absolute configuration of ginkgolide B characterized by IR- and VCD spectroscopy". Chirality 22 (2): 217–223. doi:10.1002/chir.20730.
- ^ Usai S, Grazzi L, Bussone G"Gingkolide B as migraine preventive treatment in young age: results at 1-year follow-up." Neurol Sci. 2011 May;32 Suppl 1:197-9
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