He studied guitar, piano, and music theory at the national conservatory of Greece. He continued his studies at Berklee College of Music in Boston, USA, majoring in arrangement. He has received several awards as a songwriter/producer both in Greece and Cyprus. In 1990 he settled in Athens, Greece where he began his career in the Greek music industry. In April 1993, he married Greek singer Evridiki with whom he has collaborated extensively. Together they have one son, Aggelos, who was born in 1996. The couple divorced in 2000.
In 1999, Theofanous put together boy bandONE who became very popular in Greece and Cyprus, reaching platinum sales.