Giovanni Giacomo Panciroli
He became an advocate to the Roman Curia and then accompanied Giovanni Battista Pamphili (later Pope Innocent X) during his service as nuncio to Naples and Spain. When he returned to Rome, he entered the service of the Barberini (Francesco and Antonio, nephews of Pope Urban VIII). He became chamberlain to the Pope and superintendent of the house of Cardinal Francesco Barberini.
Panciroli was elevated to cardinal on 13 July 1643 by Pope Urban VIII and was installed as Cardinal Priest at the Basilica of Santo Stefano Rotondo. The following year, Pope Urban died and Panciroli participated in the Papal conclave of 1644 which elected Pope Innocent X.
Upon Pope Innocent's election, Panciroli was appointed Cardinal Secretary of State, a position he held together with the Pope's Cardinal-Nephew Camillo Francesco Maria Pamphili until Pamphili resigned his cardinalate to marry Olimpia Aldobrandini. Upon Panciroli's death, the position was filled by Fabio Chigi who was later elected to the papal throne as Pope Alexander VII.
Panciroli died on 3 September 1651 at the Quirinal Palace in Rome.