On 21 December 1952 she married the poetPaul Celan, whom she had met in November 1951. The couple had two sons, Francois (b. 1953), who died immediately after birth, and Eric (b. 1955). As of 1967, however, she and Celan lived in separate homes.
As a graphic artist, she illustrated the works of a number of well-known poets. Many of her works are linked to the poems of Paul Celan.
Paul Celan - Gisèle Celan-Lestrange, Correspondance (1951–1970), correspondence of the pair, with selection of Paul Celan's lettres to his son Eric, edited and commented by Bertrand Badiou, with the help of Eric Celan, Paris, éd. du Seuil, 2001, 2 volumes.
John Felstiner Paul Celan: Poet, Survivor, Jew." New Haven: Yale University Press, 1995, pp. 72–73.
Katalog der Werke [Catalogue Raisonné of the artist's works], edited by Ute Bruckinger and Klaus Bruckinger in collaboration with Eric Celan and Bertrand Badiou. Tübingen; Berlin: Wasmuth 2009 ISBN 978-3-8030-3332-1