Gliadorphin

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Gliadorphin
Gliadorphin-7.svg
Identifiers
CAS number 107936-65-2
ChemSpider 26567452
Jmol-3D images Image 1
Properties
Molecular formula C43H57N9O11
Molar mass 875.97 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Gliadorphin (also known as gluteomorphin) is an opioid peptide that is formed during digestion of the gliadin component of the gluten protein. It is usually broken down into amino acids by digestion enzymes. It has been hypothesized that children with autism have abnormal leakage from the gut of this compound, which then passes into the brain and disrupts brain function.[citation needed] This is partly the basis for the gluten-free, casein-free diet. Studies of this diet have had important methodological flaws, and the scientific evidence is not adequate to make treatment recommendations.[1]

References[edit]

  1. ^ Christison GW, Ivany K (2006). "Elimination diets in autism spectrum disorders: any wheat amidst the chaff?". J Dev Behav Pediatr 27 (2 Suppl 2): S162–71. doi:10.1097/00004703-200604002-00015. PMID 16685183.