Globoidnan A

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Globoidnan A
Globoidnan A.svg
CAS number 827322-48-5 YesY
PubChem 3013628
ChemSpider 26333277 N
Jmol-3D images Image 1
Molecular formula C26H20O10
Molar mass 492.43 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Globoidnan A is a lignan found in Eucalyptus globoidea, a tree native to Australia.

The molecule has been found to inhibit the action of HIV integrase,[1] an enzyme which is responsible for the introduction of HIV viral DNA into a host's cellular DNA. It is not known that globoidnan A inhibits the action of other retroviral integrases.


  1. ^ Ovenden SP, Yu J, Wan SS, et al. (2004). "Globoidnan A: a lignan from Eucalyptus globoidea inhibits HIV integrase". Phytochemistry 65 (24): 3255–59. doi:10.1016/j.phytochem.2004.10.006. PMID 15561191.