Glutamate—tRNA(Gln) ligase

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glutamate-tRNA(Gln) ligase
Identifiers
EC number 6.1.1.24
CAS number 9068-76-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a glutamate-tRNAGln ligase (EC 6.1.1.24) is an enzyme that catalyzes the chemical reaction

ATP + L-glutamate + tRNAGlx \rightleftharpoons AMP + diphosphate + glutamyl-tRNAGlx

The 3 substrates of this enzyme are ATP, L-glutamate, and tRNAGlx, whereas its 3 products are AMP, diphosphate, and glutamyl-tRNAGlx.

This enzyme belongs to the family of ligases, to be specific those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is L-glutamate:tRNAGlx ligase (AMP-forming). This enzyme is also called glutamyl-tRNA synthetase. This enzyme participates in glutamate metabolism.

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