Glutathione oxidase

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glutathione oxidase
Identifiers
EC number 1.8.3.3
CAS number 55467-56-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a glutathione oxidase (EC 1.8.3.3) is an enzyme that catalyzes the chemical reaction

2 glutathione + O2 \rightleftharpoons glutathione disulfide + H2O2

Thus, the two substrates of this enzyme are glutathione and O2, whereas its two products are glutathione disulfide and H2O2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with oxygen as acceptor. The systematic name of this enzyme class is glutathione:oxygen oxidoreductase. This enzyme participates in glutathione metabolism. It employs one cofactor, FAD.

References[edit]

  • Kusakabe H, Kuninaka A and Yoshino H (1982). "Purification and properties of a new enzyme, glutathione oxidase from Penicillium sp.K-6-5". Agric. Biol. Chem. 46: 2057–2067. doi:10.1271/bbb1961.46.2057.