Gmina Łysomice is a rural gmina (administrative district) in Toruń County, Kuyavian-Pomeranian Voivodeship, in north-central Poland. Its seat is the village of Łysomice, which lies approximately 6 kilometres (4 mi) north of Toruń.
The gmina covers an area of 127.34 square kilometres (49.2 sq mi), and as of 2006 its total population is 8,396.
Gmina Łysomice contains the villages and settlements of Chorab, Gostkowo, Julianka, Kamionki Duże, Kamionki Małe, Kowróz, Kowrózek, Lipniczki, Lulkowo, Łysomice, Ostaszewo, Papowo Toruńskie, Papowo-Osieki, Piwnice, Różankowo, Świerczynki, Świerczyny, Turzno, Tylice, Wytrębowice, Zakrzewko and Zęgwirt.
Gmina Łysomice is bordered by the city of Toruń and by the gminas of Chełmża, Kowalewo Pomorskie, Łubianka, Lubicz and Zławieś Wielka.