Gompertz–Makeham law of mortality
The Gompertz–Makeham law states that the human death rate is the sum of an age-independent component (the Makeham term, named after William Makeham) and an age-dependent component (the Gompertz function, named after Benjamin Gompertz), which increases exponentially with age. In a protected environment where external causes of death are rare (laboratory conditions, low mortality countries, etc.), the age-independent mortality component is often negligible. In this case the formula simplifies to a Gompertz law of mortality. In 1825, Benjamin Gompertz proposed an exponential increase in death rates with age.
The Gompertz–Makeham law of mortality describes the age dynamics of human mortality rather accurately in the age window from about 30 to 80 years of age. At more advanced ages, some studies have found that death rates increase more slowly – a phenomenon known as the late-life mortality deceleration – but other studies disagree.
The decline in the human mortality rate before the 1950s was mostly due to a decrease in the age-independent (Makeham) mortality component, while the age-dependent (Gompertz) mortality component was surprisingly stable. Since the 1950s, a new mortality trend has started in the form of an unexpected decline in mortality rates at advanced ages and "de-rectangularization" of the survival curve.
The hazard function for the Gompert-Makeham distribution is most often characterised as
- Biodemography of human longevity
- Life table
- Maximum life span
- Reliability theory of aging and longevity
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- Gompertz, B. (1825). Â "On the Nature of the Function Expressive of the Law of Human Mortality, and on a New Mode of Determining the Value of Life Contingencies". Philosophical Transactions of the Royal Society 115: 513–585. doi:10.1098/rstl.1825.0026.
- Leonid A. Gavrilov & Natalia S. Gavrilova (1991) The Biology of Life Span: A Quantitative Approach. New York: Harwood Academic Publisher, ISBN 3-7186-4983-7
- Gavrilov, L.A., Gavrilova, N.S., Nosov, V.N. (1983) Human life span stopped increasing: Why? Gerontology, 29(3): 176–180.
- Gavrilov, L. A.; Nosov, V. N. (1985). "A new trend in human mortality decline: derectangularization of the survival curve". Age 8 (3): 93.
- Gavrilova N.S., Gavrilov L.A. (2011) Ageing and Longevity: Mortality Laws and Mortality Forecasts for Ageing Populations [In Czech: Stárnutí a dlouhovekost: Zákony a prognózy úmrtnosti pro stárnoucí populace]. Demografie, 53(2): 109–128.
- Jodrá, P. (2009). "A closed-form expression for the quantile function of the Gompertz–Makeham distribution". Mathematics and Computers in Simulation 79 (10): 3069–3075. doi:10.1016/j.matcom.2009.02.002.