Grace Bio-Labs
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| Industry | Biotechnology, Research Products |
|---|---|
| Founded | 1986 |
| Headquarters | Bend, Oregon, USA |
| Key people | Charles McGrath Jennipher Grudzien<br |
| Products | Oncyte Nitrocellulose Film Slide Biochips |
| Website | www.gracebio.com |
Grace Bio-Labs http://www.gracebio.com/ is a global supplier of pharmaceutical, biomedical, and biochemical research products based in Bend, Oregon, United States. They are known as pioneers in the development of the thin-cast nitrocellulose biochip (aka: nitrocellulose slide, nitrocellulose film slide)[1],[2] and the modern hybridization and incubation chambers for glass microscope slides.[3]
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[edit] History
Originally based near Detroit, Michigan, and founded by Charles McGrath in 1986, Grace Bio Labs relocated to Bend, Oregon in May, 1990.[citation needed]
[edit] Products
With the aid of SBIR funding, Grace Bio-Labs was built on two main product types. The first is the incubation chamber for cell culture and analysis; the second is the Oncyte nitrocellulose film slide. Their incubation and hybridization chambers are fluid delivery and containment products that increase sensitivity and efficiency in fluorescence and color-based protein and cell analyte assays.[4] The ONCYTE nitrocellulose microporous film http://www.gracebio.com/Products/Microarraying/Nitrocellulose_Film_Slides/ (nitrocellulose slide) is a biochip platform that captures and protects the 3-dimensional (tertiary) structure of biological material. Originally designed for tissue printing[1] and cell lysate capture, the film has flourished in proteomics. It is commonly used in automated and manual protein microarrays, and continues to increase throughput in proteomics research.[5]
Grace Bio-Labs also produces high-precision OEM and custom components for biomedical manufacturers; this constitutes a major share of their revenue.
[edit] Customer Base
Grace Bio-Labs sells to university research laboratories, biotech companies, private researchers and pharmaceutical companies. They mainly distribute to North America, Western and Central Europe, East Asia, and Southeast Asia.[citation needed]
[edit] References
- ^ a b Cytometrically coherent transfer of receptor proteins on microporous membrane. BioTechniques Vol. 11, No 3: 352-361, 1991.
- ^ High Definition cell analysis in situ using microporous films. Cell Vision, vol. 2, No 6: 499-590, 1995.
- ^ Mcgrath, Charles M.; Grudzien, Jennipher L.; Levine, Allan. Influence of Surface: Volume ratio of Reaction Chambers on Stoichiometry of Antibody-Based Reactions in Situ. Cell Vision, Vol 2, No. 2. 165-169, 1995.
- ^ [1] Janitz, M. The HybriWell Sealing System from Grace Bio-Labs. BioCompare, January 1, 03.
- ^ [2] Assay: Protein Microarrays on Nitrocellulose Slides. Genetic Engineering and Biotechnology News, Vol. 26, No 2. Mary Ann Liebert, Inc. Publishers: Jan 15, 2006.
[edit] External links
- Mcgrath, Charles; Grudzien, Jennipher. 1993. Probe Clip in Situ Assay Apparatus. U.S. Patent 5,192,503, filed May 23, 1990, and issued March 9, 1993.
- Soule, Herbert; Mcgrath, Charles. 1991. Immortal human mammary epithelial cell lines. U.S. Patent 5026637, filed February 28, 1989, and issued June 25, 1991.
- MacBeath, Gavin; Grudzien, Jennipher. 2006. Interface between substrates having microarrays and microtiter plates. US Patent 7063979, issued June 20, 2006.
