Grand Avenue was originally known as Whiskey Point Road, a muddy American Indian trail leading to the West Side of Chicago, near Western Avenue. On the Near North Side it was called Indiana Street. Thomas Jefferson Vance Owen, Chicago's first town president, is believed to have named it in 1833 after naming Chicago, "a grand place to live."
Grand Avenue is serviced by many major CTA lines. The Blue Line stops at Grand at Halsted Street and Milwaukee Avenue; this stop is the first one north of The Loop. The Red Line also stops at Grand at State Street, close to the Magnificent Mile and Navy Pier. In 2007, the CTA vowed to remodel the station, one of the busiest in the city. The No. 65 CTA bus runs along Grand Avenue, from Nordica Avenue (7000 W) to Navy Pier. The No. 33 CTA bus runs along Grand Avenue during the morning rush hour. Pace bus No. 319 serves Grand Avenue in the suburbs as well as some of the far western part of the city. It runs from Narragansett Avenue/Fullerton Avenue, in Chicago, to Wolf Road/North Avenue, in Northlake.