Grantville is an unincorporated census-designated place in southwestern Jefferson County, Kansas, United States, northeast of Topeka.
Grantville is located at 39°05′00″N 95°33′41″W / 39.083333°N 95.561367°W (39.083333, -95.561367), off U.S. Route 24. It lies 876 feet (267 m) above sea level.
Grantville has a fire station, a restaurant, a gas station and a few other local business. It also has a post office with the ZIP Code of 66429.
Grantville is served by Perry-Lecompton Unified School District 343. An early childhood center is located in Grantville.