Greatest Hits is a double-disc greatest hits album for late rapper2Pac, released by Amaru/Death Row/Jive/Interscope Records in 1998. The album's non-chronological sequence highlights 2Pac's career; the 21 popular hits, some slightly re-edited for legal reasons, are accompanied by four previously unreleased songs: the dead friends tribute "God Bless the Dead", the dedication song "Unconditional Love", the tough talk "Troublesome '96", and the album's single "Changes" also helped earn 2Pac the first and only posthumous Grammy Award nomination since for Best Rap Solo Performance. Some tracks have alternate mixes, while "California Love" makes its first proper album appearance after only being available as a single prior.
This is one of 2Pac's two albums—and one of only seven hip hop albums—to have been certified Diamond in the United States.
Of the new material, the raw-sounding "God Bless the Dead" has been the subject of the most speculation, owing to its subject matter: an apparent eulogizing of "Biggie Smalls"—a mysterious feat, since Tupac was killed six months before Biggie Smalls. The song has been misinterpreted as a clear and direct homage to Biggie. It actually pays homage to Biggy Smallz aka Big Dric of the Live Squad. It was produced by fellow Live Squad member Randy "Stretch" Walker. He is the subject of Tupac Shakur's controversial tribute song "God Bless the Dead". This person should not be confused with The Notorious B.I.G., who went by a similar name, Biggie Smalls. In addition to this, Biggy Smallz is often mistaken with Deon Evans, also known as Big D the Impossible. Evans (who is still alive) is a producer who had worked with Tupac Shakur on his earlier albums 2Pacalypse Now and Strictly 4 My N.I.G.G.A.Z.
Greatest Hits debuted at No. 3 with 268,000 and stayed in the Billboard 200 for 77 weeks.  It topped the R&B charts in the United States for 2 weeks in a row. On October 16, 2000 it was certified 9× platinum. Nearly 11 years later, in June 2011, it was certified by the RIAA for shipments of over 10 million copies, the late rapper's first ever RIAA Diamond award. The album is one of the best selling albums of all time in America.
Tupac Shakur's virtual appearance at the annual Coachella Festival on April 15 spurred a re-entry for the album on the Billboard 200 chart; it jumped in at No. 129 with 4,000 copies sold according to Nielsen SoundScan (a gain of 571% over the previous week).
The album was certified Platinum by BPI by 16 August 2002 which makes it his highest selling album in the UK.