Grepafloxacin

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Grepafloxacin
Grepafloxacin.svg
Systematic (IUPAC) name
(RS)-1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline- 3-carboxylic acid
Clinical data
AHFS/Drugs.com Multum Consumer Information
Legal status
?
Pharmacokinetic data
Protein binding 50%
Identifiers
CAS number 119914-60-2 YesY
ATC code J01MA11
PubChem CID 72474
DrugBank DB00365
ChemSpider 65391 YesY
UNII L1M1U2HC31 YesY
KEGG C11368 YesY
ChEMBL CHEMBL583 YesY
Chemical data
Formula C19H22FN3O3 
Mol. mass 359.395 g/mol
 YesY (what is this?)  (verify)

Grepafloxacin hydrochloride (trade name Raxar, Glaxo Wellcome) was an oral broad-spectrum fluoroquinolone antibacterial agent used to treat bacterial infections. Grepafloxacin was withdrawn world wide from markets owing to its side effect of lengthening the QT interval on the electrocardiogram, leading to cardiac events and sudden death.[1]

See also[edit]

References[edit]

  1. ^ Sprandel, KA.; Rodvold, KA. (2003). "Safety and tolerability of fluoroquinolones.". Clin Cornerstone. Suppl 3: S29–36. PMID 14992418.