Group-specific antigen
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Group-specific antigen (Gag) is the genetic material that codes for the core structural proteins of a retrovirus.
It comprises part of the gag-onc fusion protein.
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[edit] Gag in HIV
Gag proteins are encoded by the gag gene, and provide structural elements of the virus.
[edit] p24
p24 makes up the viral capsid.
When a Western blot test is used to detect HIV infection, p24 is one of the three major proteins tested for, along with gp120/gp160 and gp41.
[edit] p6, p7, and p17
p6 and p7 provide the nucleocapsid.
p17 provides a protective matrix (a protein that forms a scaffold during virion assembly).
[edit] See also
[edit] External links
- Diagram at stanford.edu
- MeSH gag+Protein
- MeSH gag+Genes
- MeSH gag+Gene+Products,+Human+Immunodeficiency+Virus
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