Guanine deaminase

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guanine deaminase
Identifiers
Symbol	GDA
Entrez	9615
HUGO	4212
OMIM	139260
RefSeq	NM_004293
UniProt	Q9Y2T3
Other data
EC number	3.5.4.3
Locus	Chr. 9 q21.11-21.33

Guanine deaminase (or guanine aminohydrolase) is an enzyme which converts guanine to xanthine.

guanine
xanthine. Note nitrogen replaced with oxygen. (Ignore rotation.)

[edit] External links

MeSH Guanine+deaminase

This hydrolase article is a stub. You can help Wikipedia by expanding it.

v t e Hydrolases: carbon-nitrogen non-peptide (EC 3.5)

3.5.1: Linear amides / Amidohydrolases	Asparaginase · Glutaminase · Urease · Biotinidase · Aspartoacylase · Ceramidase · Aspartylglucosaminidase · Fatty acid amide hydrolase · Histone deacetylase (Sirtuin)

3.5.2: Cyclic amides/ Amidohydrolases	Barbiturase · Beta-lactamase

3.5.3: Linear amidines/ Ureohydrolases	Arginase · Agmatinase · Protein-arginine deiminase

3.5.4: Cyclic amidines/ Aminohydrolases	Guanine deaminase · Adenosine deaminase · AMP deaminase · Inosine monophosphate synthase · DCMP deaminase · GTP cyclohydrolase I · Cytidine deaminase (AICDA, Activation-Induced (Cytidine) Deaminase)

3.5.5: Nitriles/ Aminohydrolases	Nitrilase

3.5.99: Other	Riboflavinase · Thiaminase II

B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6

Metabolism: amino acid metabolism · nucleotide enzymes

Purine metabolism

Anabolism	R5P->IMP: Ribose-phosphate diphosphokinase · Amidophosphoribosyltransferase · Phosphoribosylglycinamide formyltransferase · AIR synthetase (FGAM cyclase) · Phosphoribosylaminoimidazole carboxylase · Phosphoribosylaminoimidazolesuccinocarboxamide synthase · IMP synthase IMP->AMP: Adenylosuccinate synthase · Adenylosuccinate lyase · reverse (AMP deaminase) IMP->GMP: IMP dehydrogenase · GMP synthase · reverse (GMP reductase)

Nucleotide salvage	Hypoxanthine-guanine phosphoribosyltransferase · Adenine phosphoribosyltransferase

Catabolism	Adenosine deaminase · Purine nucleoside phosphorylase · Guanine deaminase · Xanthine oxidase · Urate oxidase

Pyrimidine metabolism

Anabolism	CAD (Carbamoyl phosphate synthase II, Aspartate carbamoyltransferase, Dihydroorotase) Dihydroorotate dehydrogenase · Orotidine 5'-phosphate decarboxylase/Uridine monophosphate synthetase CTP synthase

Catabolism	Dihydropyrimidine dehydrogenase · Dihydropyrimidinase/DPYS · Beta-ureidopropionase/UPB1

Deoxyribonucleotides

Ribonucleotide reductase · Nucleoside-diphosphate kinase · DCMP deaminase · Thymidylate synthase · Dihydrofolate reductase

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)

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