Guanosine diphosphate mannose
| Guanosine diphosphate mannose | |
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[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl dihydrogen diphosphate |
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| Identifiers | |
| CAS number | 3123-67-9 |
| PubChem | 18396 |
| ChemSpider | 17372 |
| MeSH | Guanosine+Diphosphate+Mannose |
| ChEBI | CHEBI:15820 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C16H25N5O16P2 |
| Molar mass | 605.341 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Guanosine diphosphate mannose or GDP-mannose is a nucleotide sugar that is a substrate for glycosyltransferase reactions in metabolism. This compound is a substrate for enzymes called mannosyltransferases.
[edit] Biosynthesis
GDP-mannose is produced from GTP and mannose-6-phosphate by the enzyme mannose-1-phosphate guanylyltransferase.[1]
[edit] References
- ^ Samuel G, Reeves P (2003). "Biosynthesis of O-antigens: genes and pathways involved in nucleotide sugar precursor synthesis and O-antigen assembly". Carbohydr. Res. 338 (23): 2503–19. doi:10.1016/j.carres.2003.07.009. PMID 14670712.
[edit] See also
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