Guanosine diphosphate mannose

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Guanosine diphosphate mannose
Identifiers
CAS number 3123-67-9
PubChem 18396
ChemSpider 17372 YesY
MeSH Guanosine+Diphosphate+Mannose
ChEBI CHEBI:15820 YesY
Jmol-3D images Image 1
Properties
Molecular formula C16H25N5O16P2
Molar mass 605.341 g/mol
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Guanosine diphosphate mannose or GDP-mannose is a nucleotide sugar that is a substrate for glycosyltransferase reactions in metabolism. This compound is a substrate for enzymes called mannosyltransferases.

[edit] Biosynthesis

GDP-mannose is produced from GTP and mannose-6-phosphate by the enzyme mannose-1-phosphate guanylyltransferase.[1]

[edit] References

  1. ^ Samuel G, Reeves P (2003). "Biosynthesis of O-antigens: genes and pathways involved in nucleotide sugar precursor synthesis and O-antigen assembly". Carbohydr. Res. 338 (23): 2503–19. doi:10.1016/j.carres.2003.07.009. PMID 14670712. 

[edit] See also


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