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H1 histone family, member X
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols H1FX ; H1X
External IDs OMIM602785 MGI2685307 HomoloGene4397 GeneCards: H1FX Gene
RNA expression pattern
PBB GE H1FX 204805 s at tn.png
More reference expression data
Species Human Mouse
Entrez 8971 243529
Ensembl ENSG00000184897 ENSMUSG00000044927
UniProt Q92522 Q80ZM5
RefSeq (mRNA) NM_006026 NM_198622
RefSeq (protein) NP_006017 NP_941024
Location (UCSC) Chr 3:
129.03 – 129.04 Mb
Chr 6:
87.98 – 87.98 Mb
PubMed search [1] [2]

Histone H1x is a protein that in humans is encoded by the H1FX gene.[1][2][3]

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H1 family.[3]


  1. ^ Yamamoto T, Horikoshi M (Dec 1996). "Cloning of the cDNA encoding a novel subtype of histone H1". Gene 173 (2): 281–285. doi:10.1016/0378-1119(96)00020-0. PMID 8964515. 
  2. ^ Albig W, Doenecke D (Feb 1998). "The human histone gene cluster at the D6S105 locus". Hum Genet 101 (3): 284–294. doi:10.1007/s004390050630. PMID 9439656. 
  3. ^ a b "Entrez Gene: H1FX H1 histone family, member X". 

Further reading[edit]