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H2A histone family, member V
Protein H2AFV PDB 1f66.png
PDB rendering based on 1f66.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols H2AFV ; H2A.Z-2; H2AV
External IDs MGI1924855 HomoloGene83271 GeneCards: H2AFV Gene
RNA expression pattern
PBB GE H2AFV 212205 at tn.png
PBB GE H2AFV 202487 s at tn.png
PBB GE H2AFV 212206 s at tn.png
More reference expression data
Species Human Mouse
Entrez 94239 77605
Ensembl ENSG00000105968 ENSMUSG00000041126
UniProt Q71UI9 Q3THW5
RefSeq (mRNA) NM_012412 NM_029938
RefSeq (protein) NP_036544 NP_084214
Location (UCSC) Chr 7:
44.87 – 44.89 Mb
Chr 11:
6.43 – 6.44 Mb
PubMed search [1] [2]

Histone H2A.V is a protein that in humans is encoded by the H2AFV gene.[1]

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. Several transcripts have been identified for this gene.[1]


Further reading[edit]