H2AFY2
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| H2A histone family, member Y2 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | H2AFY2; macroH2A2 | ||||||||||||
| External IDs | MGI: 3037658 HomoloGene: 10246 GeneCards: H2AFY2 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 55506 | 404634 | |||||||||||
| Ensembl | ENSG00000099284 | ENSMUSG00000020086 | |||||||||||
| UniProt | Q9P0M6 | n/a | |||||||||||
| RefSeq (mRNA) | NM_018649 | NM_207000.2 | |||||||||||
| RefSeq (protein) | NP_061119 | NP_996883.1 | |||||||||||
| Location (UCSC) | Chr 10: 71.81 – 71.87 Mb |
Chr 10: 61.2 – 61.25 Mb |
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| PubMed search | [1] | [2] | |||||||||||
Core histone macro-H2A.2 is a protein that in humans is encoded by the H2AFY2 gene.[1][2][3]
[edit] References
- ^ Chadwick BP, Willard HF (May 2001). "Histone H2A variants and the inactive X chromosome: identification of a second macroH2A variant". Hum Mol Genet 10 (10): 1101–13. doi:10.1093/hmg/10.10.1101. PMID 11331621.
- ^ Costanzi C, Pehrson JR (Jun 2001). "MACROH2A2, a new member of the MARCOH2A core histone family". J Biol Chem 276 (24): 21776–84. doi:10.1074/jbc.M010919200. PMID 11262398.
- ^ "Entrez Gene: H2AFY2 H2A histone family, member Y2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55506.
[edit] Further reading
- El Kharroubi A, Piras G, Zensen R, Martin MA (1998). "Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter.". Mol. Cell. Biol. 18 (5): 2535–44. PMC 110633. PMID 9566873. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=110633.
- Deng L, de la Fuente C, Fu P, et al. (2001). "Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones.". Virology 277 (2): 278–95. doi:10.1006/viro.2000.0593. PMID 11080476.
- Deng L, Wang D, de la Fuente C, et al. (2001). "Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA.". Virology 289 (2): 312–26. doi:10.1006/viro.2001.1129. PMID 11689053.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Lusic M, Marcello A, Cereseto A, Giacca M (2004). "Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter.". EMBO J. 22 (24): 6550–61. doi:10.1093/emboj/cdg631. PMC 291826. PMID 14657027. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=291826.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Zhang R, Poustovoitov MV, Ye X, et al. (2005). "Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA.". Dev. Cell 8 (1): 19–30. doi:10.1016/j.devcel.2004.10.019. PMID 15621527.
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