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Heterogeneous nuclear ribonucleoprotein A0
Symbols HNRNPA0 ; HNRPA0
External IDs OMIM609409 MGI1924384 HomoloGene136809 GeneCards: HNRNPA0 Gene
RNA expression pattern
PBB GE HNRPA0 201055 s at tn.png
PBB GE HNRPA0 201054 at tn.png
More reference expression data
Species Human Mouse
Entrez 10949 77134
Ensembl ENSG00000177733 ENSMUSG00000007836
UniProt Q13151 Q9CX86
RefSeq (mRNA) NM_006805 NM_029872
RefSeq (protein) NP_006796 NP_084148
Location (UCSC) Chr 5:
137.09 – 137.09 Mb
Chr 13:
58.13 – 58.13 Mb
PubMed search [1] [2]

Heterogeneous nuclear ribonucleoprotein A0 is a protein that in humans is encoded by the HNRNPA0 gene.[1][2]

This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus.[2]


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