HNT

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Neurotrimin
Identifiers
Symbols NTM ; HNT; IGLON2; NTRI
External IDs OMIM607938 MGI2446259 HomoloGene41139 GeneCards: NTM Gene
RNA expression pattern
PBB GE HNT gnf1h06520 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 50863 235106
Ensembl ENSG00000182667 ENSMUSG00000059974
UniProt Q9P121 Q8BG33
RefSeq (mRNA) NM_001048209 NM_172290
RefSeq (protein) NP_001041674 NP_758494
Location (UCSC) Chr 11:
131.24 – 132.21 Mb
Chr 9:
28.99 – 29.96 Mb
PubMed search [1] [2]

Neurotrimin is a protein that in humans is encoded by the NTM gene.[1][2]

This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple alternatively spliced variants have been found but only two variants have had their full-length sequences determined.[2]

References[edit]

  1. ^ Struyk AF, Canoll PD, Wolfgang MJ, Rosen CL, D'Eustachio P, Salzer JL (Apr 1995). "Cloning of neurotrimin defines a new subfamily of differentially expressed neural cell adhesion molecules". J Neurosci 15 (3 Pt 2): 2141–56. PMID 7891157. 
  2. ^ a b "Entrez Gene: HNT neurotrimin". 

Further reading[edit]