HOXA4

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Homeobox A4
Identifiers
Symbols HOXA4 ; HOX1; HOX1D
External IDs OMIM142953 MGI96176 HomoloGene37583 GeneCards: HOXA4 Gene
RNA expression pattern
PBB GE HOXA4 206289 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 3201 15401
Ensembl ENSG00000197576 ENSMUSG00000000942
UniProt Q00056 P06798
RefSeq (mRNA) NM_002141 NM_008265
RefSeq (protein) NP_002132 NP_032291
Location (UCSC) Chr 7:
27.17 – 27.17 Mb
Chr 6:
52.19 – 52.19 Mb
PubMed search [1] [2]

Homeobox A4, also known as HOXA4, is a protein which in humans is encoded by the HOXA4 gene.[1][2]

Function[edit]

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes.[3] Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.[1]

See also[edit]

References[edit]

  1. ^ a b "Entrez Gene: HOXA4 homeobox A4". 
  2. ^ McAlpine PJ, Shows TB (July 1990). "Nomenclature for human homeobox genes". Genomics 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146. 
  3. ^ Scott MP (November 1992). "Vertebrate homeobox gene nomenclature". Cell 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. 

Further reading[edit]

External links[edit]


This article incorporates text from the United States National Library of Medicine, which is in the public domain.