HOXB2

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Homeobox B2
Identifiers
Symbols HOXB2 ; HOX2; HOX2H; Hox-2.8; K8
External IDs OMIM142967 MGI96183 HomoloGene37584 GeneCards: HOXB2 Gene
RNA expression pattern
PBB GE HOXB2 205453 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 3212 103889
Ensembl ENSG00000173917 ENSMUSG00000075588
UniProt P14652 P0C1T1
RefSeq (mRNA) NM_002145 NM_134032
RefSeq (protein) NP_002136 NP_598793
Location (UCSC) Chr 17:
46.62 – 46.62 Mb
Chr 11:
96.35 – 96.35 Mb
PubMed search [1] [2]

Homeobox protein Hox-B2 is a protein that in humans is encoded by the HOXB2 gene.[1][2][3]

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer.[3]

See also[edit]

References[edit]

  1. ^ McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". Genomics 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146. 
  2. ^ Scott MP (Dec 1992). "Vertebrate homeobox gene nomenclature". Cell 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. 
  3. ^ a b "Entrez Gene: HOXB2 homeobox B2". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.