HOXC13

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Homeobox C13
Identifiers
Symbols HOXC13 ; ECTD9; HOX3; HOX3G
External IDs OMIM142976 MGI99560 HomoloGene7770 GeneCards: HOXC13 Gene
RNA expression pattern
PBB GE HOXC13 219832 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 3229 15422
Ensembl ENSG00000123364 ENSMUSG00000001655
UniProt P31276 P50207
RefSeq (mRNA) NM_017410 NM_010464
RefSeq (protein) NP_059106 NP_034594
Location (UCSC) Chr 12:
54.33 – 54.34 Mb
Chr 15:
102.92 – 102.93 Mb
PubMed search [1] [2]

Homeobox protein Hox-C13 is a protein that in humans is encoded by the HOXC13 gene.[1][2][3]

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the development of hair, nail, and filiform papilla.[3]

See also[edit]

References[edit]

  1. ^ McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". Genomics 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146. 
  2. ^ Scott MP (Dec 1992). "Vertebrate homeobox gene nomenclature". Cell 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. 
  3. ^ a b "Entrez Gene: HOXC13 homeobox C13". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.