HSD17B11

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Hydroxysteroid (17-beta) dehydrogenase 11
Protein HSD17B11 PDB 1yb1.png
PDB rendering based on 1yb1.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols HSD17B11 ; 17-BETA-HSD11; 17-BETA-HSDXI; 17BHSD11; DHRS8; PAN1B; RETSDR2; SDR16C2
External IDs OMIM612831 MGI2149821 HomoloGene69209 GeneCards: HSD17B11 Gene
EC number 1.1.1.62
RNA expression pattern
PBB GE HSD17B11 217989 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 51170 114664
Ensembl ENSG00000198189 ENSMUSG00000029311
UniProt Q8NBQ5 Q9EQ06
RefSeq (mRNA) NM_016245 NM_053262
RefSeq (protein) NP_057329 NP_444492
Location (UCSC) Chr 4:
87.34 – 87.39 Mb
Chr 5:
103.99 – 104.02 Mb
PubMed search [1] [2]

Estradiol 17-beta-dehydrogenase 11 is an enzyme that in humans is encoded by the HSD17B11 gene.[1][2][3][4]


References[edit]

  1. ^ Brereton P, Suzuki T, Sasano H, Li K, Duarte C, Obeyesekere V, Haeseleer F, Palczewski K, Smith I, Komesaroff P, Krozowski Z (Feb 2001). "Pan1b (17betaHSD11)-enzymatic activity and distribution in the lung". Mol Cell Endocrinol 171 (1-2): 111–7. doi:10.1016/S0303-7207(00)00417-2. PMID 11165019. 
  2. ^ Chai Z, Brereton P, Suzuki T, Sasano H, Obeyesekere V, Escher G, Saffery R, Fuller P, Enriquez C, Krozowski Z (Apr 2003). "17 beta-hydroxysteroid dehydrogenase type XI localizes to human steroidogenic cells". Endocrinology 144 (5): 2084–91. doi:10.1210/en.2002-221030. PMID 12697717. 
  3. ^ Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative". Chem Biol Interact 178 (1-3): 94–8. doi:10.1016/j.cbi.2008.10.040. PMC 2896744. PMID 19027726. 
  4. ^ "Entrez Gene: HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11". 

Further reading[edit]