HSPA1L

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Heat shock 70kDa protein 1-like
Protein HSPA1L PDB 1hjo.png
PDB rendering based on 1hjo.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols HSPA1L ; HSP70-1L; HSP70-HOM; HSP70T; hum70t
External IDs OMIM140559 MGI96231 HomoloGene130082 GeneCards: HSPA1L Gene
RNA expression pattern
PBB GE HSPA1L 210189 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 3305 15482
Ensembl ENSG00000204390 ENSMUSG00000007033
UniProt P34931 P16627
RefSeq (mRNA) NM_005527 NM_013558
RefSeq (protein) NP_005518 NP_038586
Location (UCSC) Chr 6:
31.78 – 31.78 Mb
Chr 17:
34.97 – 34.98 Mb
PubMed search [1] [2]

Heat shock 70 kDa protein 1L is a protein that in humans is encoded by the HSPA1L gene.[1][2][3]

This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein.[3]

References[edit]

  1. ^ Ito Y, Ando A, Ando H, Ando J, Saijoh Y, Inoko H, Fujimoto H (Nov 1998). "Genomic structure of the spermatid-specific hsp70 homolog gene located in the class III region of the major histocompatibility complex of mouse and man". J Biochem 124 (2): 347–53. doi:10.1093/oxfordjournals.jbchem.a022118. PMID 9685725. 
  2. ^ Ishihara M, Ohno S (Nov 1997). "Genetic influences on sarcoidosis". Eye. 11. ( Pt 2): 155–61. PMID 9349405. 
  3. ^ a b "Entrez Gene: HSPA1L heat shock 70kDa protein 1-like". 

Further reading[edit]

External links[edit]