HSPBP1

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HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
Protein HSPBP1 PDB 1xqr.png
PDB rendering based on 1xqr.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols HSPBP1 ; FES1
External IDs OMIM612939 MGI1913495 HomoloGene40827 GeneCards: HSPBP1 Gene
RNA expression pattern
PBB GE HSPBP1 202415 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 23640 66245
Ensembl ENSG00000133265 ENSMUSG00000063802
UniProt Q9NZL4 Q99P31
RefSeq (mRNA) NM_001130106 NM_024172
RefSeq (protein) NP_001123578 NP_077134
Location (UCSC) Chr 19:
55.77 – 55.79 Mb
Chr 7:
4.66 – 4.68 Mb
PubMed search [1] [2]

Hsp70-binding protein 1 is a protein that in humans is encoded by the HSPBP1 gene.[1][2][3]


Interactions[edit]

HSPBP1 has been shown to interact with HSPA8[4][5] and HSPA4.[6]

References[edit]

  1. ^ Raynes DA, Guerriero V (May 2000). "Isolation and characterization of isoforms of HspBP1, inhibitors of Hsp70". Biochim Biophys Acta 1490 (1-2): 203–7. doi:10.1016/s0167-4781(99)00238-9. PMID 10786638. 
  2. ^ Raynes DA, Guerriero V Jr (Jan 1999). "Inhibition of Hsp70 ATPase activity and protein renaturation by a novel Hsp70-binding protein". J Biol Chem 273 (49): 32883–8. doi:10.1074/jbc.273.49.32883. PMID 9830037. 
  3. ^ "Entrez Gene: HSPBP1 hsp70-interacting protein". 
  4. ^ Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature (England) 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  5. ^ Stelzl, Ulrich; Worm Uwe, Lalowski Maciej, Haenig Christian, Brembeck Felix H, Goehler Heike, Stroedicke Martin, Zenkner Martina, Schoenherr Anke, Koeppen Susanne, Timm Jan, Mintzlaff Sascha, Abraham Claudia, Bock Nicole, Kietzmann Silvia, Goedde Astrid, Toksöz Engin, Droege Anja, Krobitsch Sylvia, Korn Bernhard, Birchmeier Walter, Lehrach Hans, Wanker Erich E (Sep 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell (United States) 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. ISSN 0092-8674. PMID 16169070. 
  6. ^ Oh, Won-Kyung; Song Jaewhan (Aug 2003). "Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation". Mol. Cells (Korea (South)) 16 (1): 84–91. ISSN 1016-8478. PMID 14503850. 

Further reading[edit]