HU-243

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HU-243
HU-243 correctstructure.png
Systematic (IUPAC) name
(6aR,8S,9S,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-8,9-ditritio-7,8,10,10a-tetrahydro-6aH-benzo[c]chromen-1-ol
Clinical data
Legal status ?
Identifiers
CAS number 140835-18-3 YesY
ATC code ?
PubChem CID 3081854
Chemical data
Formula C25H40O3 
Mol. mass 388.30 g/mol

HU-243 (AM-4056) is a synthetic cannabinoid drug that is a single enantiomer of the hydrogenated derivative of the commonly used reference agonist HU-210. It is a potent agonist at both the CB1 and CB2 receptors, with a binding affinity of 0.041nM at the CB1 receptor, making it marginally more potent than HU-210, which had an affinity of 0.061nM in the same assay.[1]

See also[edit]

References[edit]

  1. ^ Stern, E.; Lambert, D. M. (2007). "Medicinal Chemistry Endeavors around the Phytocannabinoids". Chemistry & Biodiversity 4 (8): 1707–1728. doi:10.1002/cbdv.200790149. PMID 17712816.  edit