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HU-243 correctstructure.png
Systematic (IUPAC) name
Clinical data
140835-18-3 YesY
PubChem CID 3081854
Chemical data
Formula C25H40O3
388.30 g/mol

HU-243 (AM-4056) is a synthetic cannabinoid drug that is a single enantiomer of the hydrogenated derivative of the commonly used reference agonist HU-210. It is a potent agonist at both the CB1 and CB2 receptors, with a binding affinity of 0.041nM at the CB1 receptor, making it marginally more potent than HU-210, which had an affinity of 0.061nM in the same assay.[1]

See also[edit]


  1. ^ Stern, E.; Lambert, D. M. (2007). "Medicinal Chemistry Endeavors around the Phytocannabinoids". Chemistry & Biodiversity 4 (8): 1707–1728. doi:10.1002/cbdv.200790149. PMID 17712816.  edit