Haemodialysis-associated amyloidosis is a form of amyloidosis associated with chronic renal failure.
Long-term haemodialysis results in a gradual accumulation of β2 microglobulin, a serum protein, in the blood. It accumulates because it is unable to cross the dialysis filter.
Patients usually present after 5 years of dialysis rarely before that. The tendency of Dialysis associated amyloidosis is to be articular in general affecting the joints.
Low copper dialysis is theorized to prevent or delay onset.