Haloprogin was previously used in 1% topical creams as an antifungal agent. It was marketed over the counter primarily to treat tinea infections of the skin. The mechanism of action is unknown.
Haloprogin had a high incidence of side effects including: irritation, burning, vesiculation (blisters), scaling, and itching. It has since been discontinued due to the emergence of more modern antifungals with fewer side effects.
^"Haloprogin". DrugBank. University of Alberta. Nov 6, 2006. Retrieved 2007-02-17.
^Seki, S.; Nishihata, K.; Nakayama, T.; Ogawa, H. (1963). "Syntheses of Halophenyl-^|^gamma;-iodopropargyl Ethers which have High Antifungal Activity". Agricultural and Biological Chemistry27 (2): 150. doi:10.1271/bbb1961.27.150.edit