Haloprogin
From Wikipedia, the free encyclopedia
"Polik" redirects here. For other uses, see Polik (disambiguation).
 |
|
|---|---|
| Systematic (IUPAC) name | |
| 1,2,4-trichloro-5-[(3-iodoprop-2-yn-1-yl)oxy]benzene | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | Not available in U.S. |
| Routes | Topical |
| Identifiers | |
| CAS number | 777-11-7 |
| ATC code | D01AE11 |
| PubChem | CID 3561 |
| DrugBank | APRD01011 |
| ChemSpider | 3440  |
| UNII | AIU7053OWL |
| KEGG | D00339 |
| ChEMBL | CHEMBL1289 |
| Chemical data | |
| Formula | C9H4Cl3IO |
| Mol. mass | 361.39 g/mol |
| SMILES | eMolecules & PubChem |
|
|
| Physical data | |
| Melt. point | 113.5 °C (236 °F) |
| Solubility in water | insoluble mg/mL (20 °C) |
 (what is this?) (verify) |
|
Haloprogin is an antifungal drug used to treat athlete's foot and other fungal infections. It is marketed in creams under the trade names Halotex, Mycanden, Mycilan, and Polik.
[edit] Action
Haloprogin was previously used in 1% topical creams as an antifungal agent. It was marketed over the counter primarily to treat tinea infections of the skin. The mechanism of action is unknown.[1]
Haloprogin had a high incidence of side effects including: irritation, burning, vesiculation (blisters), scaling, and itching. It has since been discontinued due to the emergence of more modern antifungals with fewer side effects.[2]
[edit] References
- ^ "Haloprogin". Drugs@FDA. Food and Drug Administration. http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction=Search.Overview&DrugName=HALOTEX. Retrieved 2007-02-17.
- ^ "Haloprogin". DrugBank. University of Alberta. Nov 06, 2006. http://redpoll.pharmacy.ualberta.ca/drugbank/cgi-bin/getCard.cgi?CARD=APRD01011.txt. Retrieved 2007-02-17.
|
||||||||||||||||||||||||||||||||||||||||||
 |
This antiinfective drug article is a stub. You can help Wikipedia by expanding it. |
 |
This dermatologic drug article is a stub. You can help Wikipedia by expanding it. |
