Haloprogin

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"Polik" redirects here. For other uses, see Polik (disambiguation).
Haloprogin
Haloprogin.png
Systematic (IUPAC) name
1,2,4-trichloro-5-[(3-iodoprop-2-yn-1-yl)oxy]benzene
Clinical data
Legal status Not available in U.S.
Routes Topical
Identifiers
CAS number 777-11-7 YesY
ATC code D01AE11
PubChem CID 3561
DrugBank DB00793
ChemSpider 3440 YesY
UNII AIU7053OWL YesY
KEGG D00339 YesY
ChEMBL CHEMBL1289 YesY
Chemical data
Formula C9H4Cl3IO 
Mol. mass 361.39 g/mol
Physical data
Melt. point 113.5 °C (236 °F)
Solubility in water insoluble mg/mL (20 °C)
 YesY (what is this?)  (verify)

Haloprogin is an antifungal drug used to treat athlete's foot and other fungal infections. It is marketed in creams under the trade names Halotex, Mycanden, Mycilan, and Polik.

Action[edit]

Haloprogin was previously used in 1% topical creams as an antifungal agent. It was marketed over the counter primarily to treat tinea infections of the skin. The mechanism of action is unknown.[1]

Haloprogin had a high incidence of side effects including: irritation, burning, vesiculation (blisters), scaling, and itching. It has since been discontinued due to the emergence of more modern antifungals with fewer side effects.[2]

References[edit]

  1. ^ "Haloprogin". Drugs@FDA. Food and Drug Administration. Retrieved 2007-02-17. 
  2. ^ "Haloprogin". DrugBank. University of Alberta. Nov 6, 2006. Retrieved 2007-02-17.