|Possible time of origin||10 to 15 thousand years ago|
|Possible place of origin||Beringia: Either East Asia or North America|
|Descendants||Q-M19, Q-M194, Q-M199, Q-PAGES104, Q-PAGES131, Q-L663, Q-SA01, Q-L766, Q-L883, and Q-L888|
|Defining mutations||M3 (rs3894)|
In human population genetics, haplogroups define the major lineages of direct paternal (male) lines back to a shared common ancestor in Africa. Haplogroup Q-M3 (Y-DNA) is a Y-chromosome DNA haplogroup. Haplogroup Q-M3 is a subclade of Haplogroup Q-L54.
Haplogroup Q-M3 was previously known as Haplogroup Q3. In 1996 the research group at Stanford University headed by Dr. Peter Underhill first discovered the SNP that was to become known as M3. At the time, it was called DYS191. Later studies completed the genetic bridge by determining that Q-M3 was related to Q-M242-bearing populations who traveled through Central Asia to East Asia.
Origin and Distribution 
Haplogroup Q-M3 is one of the Y-Chromosome haplogroups linked to the indigenous peoples of the Americas. To date, such lineages also include Q-M242 branches (Q-M346, Q-L54, Q-P89.1, Q-NWT01, and Q-Z780) and haplogroup C-M130 branches (C-M217 and C-P39) which are almost exclusively found in North America. Haplogroup Q-M3 is defined by the presence of the rs3894 (M3) single-nucleotide polymorphism (SNP). Q-M3 occurred on the Q-L54 lineage roughly 10-15 thousand years ago as the migration into the Americas was underway. There is some debate as to on which side of the Bering Strait this mutation occurred, but it definitely happened in the ancestors of the indigenous peoples of the Americas.
The Americas 
Populations carrying Q-M3 are widespread throughout the Americas. Since the discovery of Q-M3 several subclades of Q-M3 bearing populations have been discovered in the Americas as well. An example is in South America where some populations have a high prevalence of SNP M19 which defines subclade Q-M19. M19 has been detected in 59% of Amazonian Ticuna men and in 10% of Wayuu men. Subclades Q-M19 and Q-M199 appear to be unique to South American populations and suggests that population isolation and perhaps even the establishment of tribes began soon after migration into the Americas.
|Kets||Vajda 2012||>90%||M3 (Q1a3a)|
|Selkups||Vajda 2012||65%||M3 (Q1a3a)|
The Q-M3 lineage has not been detected in the European population.
Subclade Distribution 
Q-M194 It has only been found in South American populations.
Q-M199 This lineage has only been found in South American populations.
Q-L663 This lineage was discovered by citizen scientists. It may be linked to indigenous populations in the Southwestern United States and Mexico.
Q-L766 This lineage was discovered by citizen scientists. It may be linked to indigenous populations in the Southwestern United States and Mexico.
Q-L883 This lineage was discovered by citizen scientists.
Q-L888 This lineage was discovered by citizen scientists.
Associated SNP's 
Q-M3 is defined by the SNPs M3 and L341.2.
This is Thomas Krahn at the Genomic Research Center's Draft tree Proposed Tree for haplogroup Q-M3.
- M3, L341.2
- M199, P106, P292
- PAGES104, PAGES126
- L766, L767
- L883, L884, L885, L886, L887
- L888, L889, L890, L891
- M3, L341.2
See also 
Y-DNA Q-M242 Subclades 
Y-DNA Backbone Tree 
|Evolutionary tree of human Y-chromosome DNA (Y-DNA) haplogroups|
- Wells, R. Spencer (2002). The Journey of Man: A Genetic Odyssey. Princeton, NJ [u.a.] : Princeton Univ. Press. ISBN 069111532X.
- Ruiz-Linares, A.; Ortiz-Barrientos, D.; Figueroa, M.; Mesa, N.; Munera, J. G.; Bedoya, G.; Velez, I. D.; Garcia, L. F. et al. (1999). "Microsatellites provide evidence for Y chromosome diversity among the founders of the New World". Proceedings of the National Academy of Sciences 96 (11): 6312. doi:10.1073/pnas.96.11.6312.
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-  2012 Dene-Yeniseian Workshop
- (2003) "Y-Chromosome Evidence for Differing Ancient Demographic Histories in the Americas," (pdf) Maria-Catira Bortolini, Francisco M. Salzano
- "Theodore G. Schurr".