Possible time of origin 23,600 to 54,900 YBP
Possible place of origin
Near East or South Asia
Defining mutations 73, 11719
human mitochondrial genetics, Haplogroup R0 (formerly known as Haplogroup pre-HV ) is a [3 ] mitochondrial DNA (mtDNA) haplogroup.
Haplogroup R0 derives from the
macro-haplogroup R. It is an ancestral haplogroup to R0a and Haplogroup HV (and therefore to Haplogroup H and Haplogroup V).
Distribution [ edit ]
R0 occurs frequently in the Arabian Plate with its highest frequency in Socotri (Population 50,000 Yemen) 38% and its also found in a high frequency in the [4 ] Kalash (Population 6,000 in Pakistan) with 23% smaller frequency in [5 ] North Africa, the Horn of Africa, Anatolia, Iranian Plateau & Dalmatia. Its greater variety in the Arabian Plate suggests R0a originated in and spread from there.
Subclades [ edit ]
This phylogenetic tree of haplogroup R0 subclades is based on the paper by Mannis van Oven and Manfred Kayser
Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation and subsequent published research. [2 ]
R0 or pre-HV
R0a or (preHV)1
R0a1 or (preHV)1a
R0a2 or (preHV)1b
See also [ edit ]
References [ edit ]
^ Soares, P; Ermini, L; Thomson, N; Mormina, M; Rito, T; Röhl, A; Salas, A; Oppenheimer, S et al. (2009). "Correcting for Purifying Selection: An Improved Human Mitochondrial Molecular Clock". American Journal of Human Genetics 84 (6): 740–59. doi: 10.1016/j.ajhg.2009.05.001. PMC 2694979. PMID 19500773.
^ a b van Oven, Mannis; Manfred Kayser (13 Oct 2008). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation 30 (2): E386–E394. doi: 10.1002/humu.20921. PMID 18853457 . Retrieved 2009-05-20.
^ Haplogroup H Sub-clades, Family Tree DNA
^ Viktor Cerny et al. 2008, Out of Arabia—The Settlement of Island Soqotra as Revealed by Mitochondrial and Y Chromosome Genetic Diversity.
^ Quintana-Murci, Lluís et al. (2004). "Where West Meets East: The Complex mtDNA Landscape of the Southwest and Central Asian Corridor.". American Journal of Human Genetics 74: 2004. doi: 10.1086/383236. PMC 1181978. PMID 15077202.
External links [ edit ]