Haplogroup R-M207

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Haplogroup R-M207

Haplogroup R (Y-DNA).jpg

Possible time of origin 26,800 (24,000 [1] - 34,300) years ago (Karafet 2008)
Possible place of origin South Asia or Central Asia
Ancestor P-M45
Descendants Paragroup R-M207, R-M173, R-M479
Defining mutations R = M207 (UTY2), P224, P227, P229, P232, P280, P285, S4, S8, S9 and V45 (ISOGG 2010)

In molecular evolution, a haplogroup is a group of similar haplotypes that share a common ancestor having the same single nucleotide polymorphism (SNP) mutation in all haplotypes. Haplogroup R-M207 is a Y-chromosome DNA haplogroup. It marks a major split in paleolithic lineages some descendant lines are common throughout Europe, Central Asia and South Asia, and also common in parts of the West Asia and Africa. Others are primarily from West Asia and South Asia. This line is a descendant of haplogroup P-M45.


This haplogroup is believed to have arisen around 24,000–34,000 years ago (Karafet 2008), somewhere in South Asia or Central Asia, where its ancestor Haplogroup P-M45 is most often found at polymorphic frequencies (Shirs 2001). The most recent common ancestor (TMRCA) of haplogroup R lived around 19 thousand years before present, the addition of Central Asian chromosomes contributes a sequence to the deepest subclade of R1b-M269, while another, in a Bhutanese individual, forms an outgroup almost as old as the R1a/R1b split.[1]

Haplogroup R* was found in the remains of a Palaeolithic boy MA-1 (Mal'ta) near Lake Baikal in Siberia, dating to 24,000 years ago.[2]


Y-haplogroup R-M207 is found throughout Europe, South Asia and Central Asia. Small frequencies are found in Indigenous Australians (Kayser 2003). It also occurs in the Caucasus and Siberia.

Subclade distribution[edit]

Paragroup R-M207[edit]

Haplogroup R* Y-DNA (xR1,R2) was found in 24,000-year old-remains from Mal'ta in Siberia near Lake Baikal.[3]


Spread of Haplogroup R-M173 in Native populations.

R-M173 is common throughout Europe, and Eurasia (West Asia, Central Asia) and was historically known as R1. It has many branches (Semino 2000 and Rosser 2000). It is notably found among the Shors (19.6%), Teleuts (12.8%), Tofalars (12.5%), Khakassians (7.6%), Russians (6.8%) and Evenks (6.0%).[4] In lower frequencies it is also found among the Mongols (4.3%), Kalmyks (2.9%), Todjins (2.8%), Altai Kiji (1.1%), Tuvinians (0.9%) and Buryats (0.8%).[4]

In the Americas, it is not a pre-Columbian founding lineage. The presence of R-M173 in the Americas is probably partly or wholly the result of Eurasian admixture (Malhi 2008 and Lell 2002). However, it is the second most common haplogroup in Indigenous peoples of the Americas following haplogroup Q-M242, and spreads specially in Algonquian peoples from United States and Canada (Malhi 2008).


Main article: Haplogroup R-M479

Haplogroup R-M479 is defined by the presence of the marker M479. The paragroup for the R-M479 lineage is found in Pakistan North, Portugal, Spain, Tatars (Bashkortostan, Russia), Italy North, and Ossetians South (South Caucasus) (Myres 2010).

Phylogenetic trees[edit]

There are several confirmed and proposed phylogenetic trees available for haplogroup R-M207. The scientifically accepted one is the Y-Chromosome Consortium (YCC) one published in Karafet 2008 and subsequently updated. A draft tree that shows emerging science is provided by Thomas Krahn at the Genomic Research Center in Houston, Texas.

The Genomic Research Center draft tree[edit]

This is Thomas Krahn at the Genomic Research Center's Draft tree Proposed Tree for haplogroup R-M207. The first three levels of subclades are shown. Additional detail is provided on the linked branch article pages (Krahn 2012).

  • P-M45
    • R-M207 M207, P224, P227, P229, P232, P280, P285, L248.2, L1031
      • R-M173 M173, M306, P231, P233, P234, P236, P238, P241, P242, P245, P286, P294
      • R-M479 M479

See also[edit]


Y-DNA R-M207 subclades[edit]

Y-DNA backbone tree[edit]

Evolutionary tree of human Y-chromosome DNA (Y-DNA) haplogroups
MRC Y-ancestor
A00 A0'1'2'3'4
A0 A1'2'3'4
A1 A2'3'4
I J LT(K1) K (K2)
L T MPS (K2b) X (K2a)
  1. ^ van Oven M, Van Geystelen A, Kayser M, Decorte R, Larmuseau HD (2014). "Seeing the wood for the trees: a minimal reference phylogeny for the human Y chromosome". Human Mutation 35 (2): 187–91. doi:10.1002/humu.22468. PMID 24166809. 
  R 207   1b1b2a1a


  1. ^ Hallast, P. et al. 2014. The Y-chromosome tree bursts into leaf: 13,000 high-confidence SNPs covering the majority of known clades. Molecular Biology & Evolution. Oxford Journals.
  2. ^ Raghavan, M. et al. 2014. Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans, Nature, 505, 87–91.
  3. ^ Raghavan, Maanasa; Pontus Skoglund, Kelly E. Graf, Mait Metspalu, Anders Albrechtsen, Ida Moltke, Simon Rasmussen, Thomas W. Stafford Jr, Ludovic Orlando, Ene Metspalu, Monika Karmin, Kristiina Tambets, Siiri Rootsi, Reedik Mägi, Paula F. Campos, Elena Balanovska, Oleg Balanovsky, Elza Khusnutdinova, Sergey Litvinov, Ludmila P. Osipova, Sardana A. Fedorova, Mikhail I. Voevoda, Michael DeGiorgio, Thomas Sicheritz-Ponten, Søren Brunak et al. (2 January 2014). "Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans". Nature 505 (7481): 87–91. doi:10.1038/nature12736. PMC 4105016. PMID 24256729. 
  4. ^ a b Miroslava Derenko et al 2005, Contrasting patterns of Y-chromosome variation in South Siberian populations from Baikal and Altai-Sayan regions. Hum Genet (2006) 118: 591–604. doi:10.1007/s00439-005-0076-y

Further reading[edit]

  • The History and Geography of Human Genes. Princeton University Press. 1994. ISBN 0-691-08750-4. 
  • Anjana, Saha, Swarkar, Sharma, Audesh, Bhat, Awadesh, Pandit, Ramesh, Bamezai (2005). "Genetic affinity among five different population groups in India reflecting a Y-chromosome gene flow". J Hum Genet 50 (1): 49–51. doi:10.1007/s10038-004-0219-3. PMID 15611834. 

External links[edit]

Discussion and projects