The Harding House-Walker Missionary Home is a historic house at 161-163 Grove Street in the Auburndale village of Newton, Massachusetts. The 2.5 story wood frame house was built c. 1850, and is a well preserved example of Italianate styling. It was built for Rev. Sewell Harding, a significant early speculator in Auburndale real estate. Harding sold the house in the 1860s; after serving as a dormitory for Lasell Junior College for several decades, it was acquired in 1925 by the Walker Home for Missionary Children, an organization established by Harding's daughter, Eliza Walker.