Since the 19th century, the number of doctors, hospitals, and medical organizations in and around Harley Street has greatly increased. Records show that there were around 20 doctors in 1860, 80 by 1900, and almost 200 by 1914. When the National Health Service was established in 1948, there were around 1,500. Today, there are more than 3,000 people employed in the Harley Street area, in clinics, medical and paramedical practices, and hospitals such as The Harley Street Clinic and The London Clinic.
It has been speculated that doctors were originally attracted to the area by the development of commodious housing and central proximity to the important railway stations of Paddington, Kings Cross, St Pancras, Euston and, later, Marylebone. The nearest Tube stations are Regent's Park and Oxford Circus.
Harley Street is part of the Howard de Walden Estate.
Many famous people have lived or practised in Harley Street, including the Victorian prime minister William Ewart Gladstone, the artist J. M. W. Turner, and Lionel Logue, who successfully treated George VI for his pronounced stuttering.
Queen's College, founded in 1848 and one of the oldest girls' schools in England, is situated on Harley Street.
- List of eponymous roads in London
- Macquarie Street, Sydney
- Rodney Street, the Harley Street of the North, in Liverpool
- Welbeck Street
- Wimpole Street
- History of Harley Street at Harley Street Guide (commercial website)
- Linda Hopkins (31 December 2008). False Self: The Life of Masud Khan. Karnac Books. pp. 9–. ISBN 978-1-78049-403-6.
- Henry Benjamin Wheatley; Peter Cunningham (24 February 2011). London Past and Present: Its History, Associations, and Traditions. Cambridge University Press. pp. 192–. ISBN 978-1-108-02807-3.
- Grantly Dick-Read
- David J. Apple (2006). Sir Harold Ridley and His Fight for Sight: He Changed the World So that We May Better See it. SLACK Incorporated. pp. 50–. ISBN 978-1-55642-786-2.
- Christopher Hibbert; John Keay; Julia Keay (23 March 2010). The London Encyclopaedia. Macmillan. ISBN 978-1-4050-4925-2.
- Modern English Biography: Containing Many Thousand Concise Memoirs of Persons who Have Died Between the Years 1851-1900