The Harrison High School mascot is the Golden Goblin with blue and gold as its school colors. The Harrison Golden Goblins participate in interscholastic activities In the 5A West Conference under the administration of the Arkansas Activities Association. The Golden Goblins sport teams include baseball, basketball (boys/girls), cheerleading, cross country (boys/girls), debate, football, golf (boys/girls), soccer (boys/girls), softball, speech, tennis (boys/girls), track (boys/girls), and volleyball.
Cross country: The girls cross country team is one of the state's most successful with nine state championships between 1993 and 2003, including a state record eight consecutive titles (1993–2000).
Basketball: The girls basketball team captured three consecutive state championships in 2000, 2001, and 2002.
Baseball: The baseball team won its first state baseball championship in 2008, with head coach Kirk Bock being awarded the District 6 Baseball Coach of the Year by the National High School Baseball Coaches of America.
Soccer: As of the 2012 season, the boys soccer team is the state's only boys team with six state soccer championships winning 5A classification titles in spring 2002–2006 and 2008. The girls team are 3-time state champions with 5A titles in 2002, 2004 and 2011. Harrison boasts the 2010 NSCAA Arkansas Girls High School Player of the Year award winner.