From Wikipedia, the free encyclopedia
Jump to: navigation, search
CAS number 1805-85-2
PubChem 442246
ChemSpider 390731 YesY
Jmol-3D images Image 1
Molecular formula C21H27NO5
Molar mass 373.19 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 YesY (verify) (what is: YesY/N?)
Infobox references

Hasubanonine is a member of the hasubanan family of alkaloids. The alkaloid with an isoquinoline substructure has the molecular formula of C21H27NO5.[1] The enantiomer of the natural product is being studied as a potential painkiller.[2] Hasubanonine is structurally related to the morphinan class of opioid analgesics.

The enantioselective total synthesis of (–)-hasubanonine and related natural products, (-)-runanine, (-)-delavayine, and (+)-periglaucine B were first achieved by Prof. Seth Herzon and co-workers at Yale University in 2011. [3]


  1. ^ Hasubanonine
  2. ^ Deseret News - Chemists hoping to ease pain
  3. ^ Herzon, S. B.; Calandra, N. A.; King, S. M. Angew. Chem. Int. Ed. 2011, 1:5 (12 September 2011), doi:10.1002/anie.201102226