Constantino wrote "Hawak Kamay" at age 14, inspired by a cousin who had left their hometown to live away from her. She performed the song for the first time live on Pinoy Dream Academy. During that time, she sang the song along with her fellow contestants Ronnie Liang, Davey Langit, Joan Ilagan and Jun Hirano. Following public demand, the song was released by Star Records. The song is the most successful single to date in Constantino's career.
Constantino first performed this song on Pinoy Dream Academy, together with her fellow contestants Ronnie Liang, Davey Langit, Joan Ilagan and Jun Hirano. She has performed the song several times on ASAP. In September 2009, she performed the song on Umagang Kay Ganda as a tribute for the victims of Typhoon Ondoy (international name Ketsana). In August 2011, she performed a medley of "Hawak Kamay" and her song "Lapit" on Eat Bulaga!. On December 9, 2011, Constantino and American singer/songwriter David DiMuzio performed a duet of "Hawak Kamay (I'm By Your Side)" in Taglish on ASAP Rocks.