"He Knows You Know" is Marillion's second single, with "Charting the Single" as the B-side. It was released from their first album, Script for a Jester's Tear, and peaked at number 35 on the UK Singles Chart. The song's theme is drug abuse, and alludes particularly to intravenous drug use. In a live situation lead vocalist Fish would often introduce it as "The Drug Song" and that it was inspired by drug use while working at the Job/Benefits centre in Aylesbury where Fish was working.
As with all Marillion songs during this period, the lyrics were written by Fish. The music video for this song features Fish struggling in a straitjacket having visions of a Jackson's Chameleon as featured on the album artwork of Marillion's first three albums.
"He Knows You Know" was the only 12-inch single from Marillion's first three albums that was never produced as a picture disk. The song was supposed to be performed live on Top Of The Pops in 1983 but as Fish explains on the Recital of the Script concert this never happened, however a live on TV version was later recorded for the BBCOxford Road Show.
A CD replica of the single was also part of a collectors box-set released in July 2000 which contained Marillion's first twelve singles and was re-issued as a 3-CD set in 2009 (see The Singles '82-'88).