"Heart Trouble" was the third official release by the Detroitsoul group The Parliaments. The single was released in 1965 by Golden World Records (GW-46). "Heart Trouble" was the only single that the Parliaments recorded for the label.
"Heart Trouble" was later re-worked in 1973 under the title "You Can't Miss What You Can't Measure", featured on the Funkadelic album Cosmic Slop. Another version of the track was recorded approximately three years earlier, yet did not surface until the 2008 release of the CD "Toys". The b-side, "That Was My Girl" was re-recorded in 1972 and was featured on America Eats Its Young.