Little is known about her life. In 1162, she initiated the founding of the Cistercian monastery Altzella Abbey near Nossen. This would provide the Margraves of Meissen with bailiwick rights over the location where they buried deceased family members and erected momrials. Altzella was, due to its location, also an important starting point of residential development in Meissen.
Hedwig has been described as generally a strong woman, who exerted a significant influence on her husband. It was alleged that she was the one that convinced him to alter the order of succession, so that her husband would not be succeeded by his eldest son Albrecht, as normal, but by his youngest son Dietrich. Albert did not accept this change and started a war against his father and brother. In 1189, he even took his father prisoner. The conflict ended when Albert died in 1195.