Helen Tobias was born in Suure-Jaani, Estonia on June 11, 1919. Tobias was the youngest daughter of Estonian composer, Rudolf Tobias, born seven months after his death. She studied music composition at the Tallinn Conservatoire, which is now known as the Estonian Academy of Music and Theatre, under Artur Kapp and Heino Eller. She also received training from August Topman and graduated from the Conservatoire as an organist in 1943. She later studied at the Berlin University of Music as well.
During World War II, she met her future husband, William Duesberg, a journalist who was repeatedly imprisoned for writing stories critical of Adolf Hitler. Shortly after the war, Duesberg died of a heart attack in a Stuttgart courtroom while preparing to testify against several Nazi war criminals.
Tobias-Duesberg moved to the United States from Estonia, which was then part of the Soviet Union, in 1951. She began composing music and performing at several churches in New York City. She composed chamber, vocal and symphonic pieces, the most famous of which may be Requiem, which was composed for orchestra, mixed choir and soloists.
Meanwhile, she composed violin and cello sonatas, string quartets, song cycles, concertos, and a wide range of choral works. Her compositions have been performed on major concert stages in the U.S., Canada, and Europe as well as the Aspen, Ravinia and Spoleto festivals.
During a cultural backlash against classical music in the 1960s and '70s, American conductor Leonard Bernstein described Tobias-Duesberg as a female composer who "dares to be original and musical at the same time, while all the men run around writing intellectual cacophony."
- Ballaade orkestrile (Ballade on Estonian and Carelian Folktunes) for orchestra
- Concert Piece for cello and chamber orchestra
- Chamber music
- Koraal-prelüüdid for violin, cello and piano
- Sextet for brass
- Sonata for violin and piano
- Sonata in G for cello and piano
- String Quartet No. 2
- Trio for violin, flute and piano
- Trio in C for violin, viola (or cello) and piano
- Classical Suite
- Parafraas eesti rahvalaulude viisidele (Prelude on Estonian Folksongs)
- 4 Preludes
- Sa tulid nagu päikene for voice and piano
- Missa brevis for mixed chorus and keyboard accompaniment
- Psalm 102 for mixed chorus and organ
- Requiem for female chorus and keyboard accompaniment
- Vaimulik õhtu-muusika (Sacred Evening Service) for mixed chorus, baritone, soprano and organ