Lipohemarthrosis (blood and fat in the joint space) seen in a person with a subtle tibial plateau fracture. The arrow indicates a fluid level between the upper fat component and the lower blood component.
In hemophilia it may occur spontaneously, and recurrent hemarthroses are a major cause of disability in that patient group due to hemophilic arthropathy, requiring synovectomy, joint replacement and increased medical therapy to prevent further bleeding episodes, although it is controversial whether clotting factor administration adequately prevents hemarthroses.
^Stobart K, Iorio A, Wu JK (2006). Stobart, Kent, ed. "Clotting factor concentrates given to prevent bleeding and bleeding-related complications in people with hemophilia A or B". Cochrane Database Syst Rev (2): CD003429. doi:10.1002/14651858.CD003429.pub3. PMID16625581.
^Goldberg A, Stansby G "Surgical Talk" 2nd edition