Hennenman, which was built as a single railway station, was formerly denoted as Ventersburg Road. In 1927, it was renamed after local Afrikaner P.F. Hennenman, from Swartpan Farm.
In 1944, black South Africans were confined to a segregated enclave in southern Hennenman. During apartheid, this area was cleared by order of the government and nearly all then-residents relocated to a new township some fifteen kilometres away, Vergenoeg (now Phomolong).